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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
16.97
Human Site:
S189
Identified Species:
37.33
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
S189
R
V
Q
H
M
D
L
S
N
S
V
I
E
V
S
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
H148
D
L
T
G
K
N
L
H
P
D
V
T
G
R
L
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
S187
R
V
Q
H
M
D
L
S
N
S
V
I
E
V
S
Dog
Lupus familis
XP_546346
749
81658
S514
R
V
Q
H
M
D
L
S
N
S
V
I
D
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
S189
R
V
Q
H
M
D
L
S
N
S
V
I
N
V
S
Rat
Rattus norvegicus
Q9QZH7
276
30442
C46
F
L
D
V
V
T
L
C
R
C
A
Q
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
S210
R
V
Q
H
M
D
L
S
N
C
T
V
S
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
V244
I
V
R
R
G
V
L
V
I
R
L
A
Q
T
S
Honey Bee
Apis mellifera
XP_395497
484
54314
K253
L
T
D
G
Y
I
S
K
L
Q
Y
L
D
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
P202
S
A
M
E
E
G
E
P
D
D
L
D
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
I130
D
L
S
K
S
S
K
I
T
D
H
S
L
Y
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
6.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
20
N.A.
N.A.
80
N.A.
N.A.
N.A.
40
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% C
% Asp:
19
0
19
0
0
46
0
0
10
28
0
10
19
0
0
% D
% Glu:
0
0
0
10
10
0
10
0
0
0
0
0
19
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
10
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
46
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
10
10
0
0
37
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
28
0
0
0
0
73
0
10
0
19
10
10
10
10
% L
% Met:
0
0
10
0
46
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
46
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
46
0
0
0
0
0
0
10
0
10
10
0
0
% Q
% Arg:
46
0
10
10
0
0
0
0
10
10
0
0
0
10
19
% R
% Ser:
10
0
10
0
10
10
10
46
0
37
0
10
19
19
64
% S
% Thr:
0
10
10
0
0
10
0
0
10
0
10
10
0
10
0
% T
% Val:
0
55
0
10
10
10
0
10
0
0
46
10
10
46
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _